Brain structure and intragenic DNA methylation are correlated, and predict executive dysfunction in fragile X premutation females

DNA methylation of the Fragile X mental retardation 1 (FMR1) exon 1/intron 1 boundary has been associated with executive dysfunction in female carriers of a FMR1 premutation (PM: 55–199 CGG repeats), whereas neuroanatomical changes have been associated with executive dysfunction in PM males. To our...

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Udgivet i:Transl Psychiatry
Main Authors: Shelton, A L, Cornish, K M, Kolbe, S, Clough, M, Slater, H R, Li, X, Kraan, C M, Bui, Q M, Godler, D E, Fielding, J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290342/
https://ncbi.nlm.nih.gov/pubmed/27959330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.250
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