T‐bet‐mediated Tim‐3 expression dampens monocyte function during chronic hepatitis C virus infection

Hepatitis C virus (HCV) induces a high rate of chronic infection via dysregulation of host immunity. We have previously shown that T‐cell immunoglobulin and mucin domain protein‐3 (Tim‐3) is up‐regulated on monocyte/macrophages (M/Mφ) during chronic HCV infection; little is known, however, about the...

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Publicado en:Immunology
Autores principales: Yi, Wenjing, Zhang, Peixin, Liang, Yan, Zhou, Yun, Shen, Huanjun, Fan, Chao, Moorman, Jonathan P., Yao, Zhi Q., Jia, Zhansheng, Zhang, Ying
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290233/
https://ncbi.nlm.nih.gov/pubmed/27809352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12686
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