Pifithrin-µ prevents cisplatin-induced chemobrain by preserving neuronal mitochondrial function

Cognitive impairment termed chemobrain is a common neurotoxicity associated with chemotherapy treatment, affecting an estimated 78% of patients. Prompted by the hypothesis that neuronal mitochondrial dysfunction underlies chemotherapy-induced cognitive impairment (CICI), we explored the efficacy of...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Chiu, Gabriel S., Maj, Magdalena A., Rizvi, Sahar, Dantzer, Robert, Vichaya, Elisabeth G., Laumet, Geoffroy, Kavelaars, Annemieke, Heijnen, Cobi J.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290207/
https://ncbi.nlm.nih.gov/pubmed/27879267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1817
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