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Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency
Glioblastoma Multiforme (GBM) is characterized by high cancer cell heterogeneity and the presence of a complex tumor microenvironment. Those factors are a key obstacle for the treatment of this tumor type. To model the disease in mice, the current strategy is to grow GBM cells in serum-free non-adhe...
Gespeichert in:
| Veröffentlicht in: | Oncogene |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5290038/ https://ncbi.nlm.nih.gov/pubmed/27345406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.230 |
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