The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit

The genetic consequences of population bottlenecks on patterns of deleterious genetic variation in human populations are of tremendous interest. Based on exome sequencing of 18 Greenlandic Inuit we show that the Inuit have undergone a severe ∼20,000-year-long bottleneck. This has led to a markedly m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Pedersen, Casper-Emil T., Lohmueller, Kirk E., Grarup, Niels, Bjerregaard, Peter, Hansen, Torben, Siegismund, Hans R., Moltke, Ida, Albrechtsen, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289852/
https://ncbi.nlm.nih.gov/pubmed/27903613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.193821
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados