RGS9-2 modulates D(2) dopamine receptor-mediated Ca(2+) channel inhibition in rat striatal cholinergic interneurons

Regulator of G protein signaling (RGS) proteins negatively regulate receptor-mediated second messenger responses by enhancing the GTPase activity of Gα subunits. We describe a receptor-specific role for an RGS protein at the level of an individual brain neuron. RGS9-2 and Gβ(5) mRNA and protein comp...

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Main Authors: Cabrera-Vera, Theresa M., Hernandez, Salvador, Earls, Laurie R., Medkova, Martina, Sundgren-Andersson, Anna K., Surmeier, D. James, Hamm, Heidi E.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2004
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC528982/
https://ncbi.nlm.nih.gov/pubmed/15534226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407416101
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