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Induction of antiviral immunity requires Toll-like receptor signaling in both stromal and dendritic cell compartments

Pattern recognition by Toll-like receptors (TLRs) is known to be important for the induction of dendritic cell (DC) maturation. DCs, in turn, are critically important in the initiation of T cell responses. However, most viruses do not infect DCs. This recognition system poses a biological problem in...

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Bibliografiske detaljer
Main Authors: Sato, Ayuko, Iwasaki, Akiko
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC528964/
https://ncbi.nlm.nih.gov/pubmed/15534227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406268101
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