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L-type voltage-operated calcium channels contribute to astrocyte activation in vitro

We have found a significant upregulation of L-type voltage-operated Ca(++) channels (VOCCs) in reactive astrocytes. To test if VOCCs are centrally involved in triggering astrocyte reactivity, we used in vitro models of astrocyte activation in combination with pharmacological inhibitors, siRNAs and t...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Cheli, VT, Santiago González, DA, Smith, J, Spreuer, V, Murphy, GG, Paez, PM
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289280/
https://ncbi.nlm.nih.gov/pubmed/27247164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23013
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