Power Calculations and Placebo Effect for Future Clinical Trials in Progressive Supranuclear Palsy

BACKGROUND: Two recent randomized, placebo-controlled trials of putative disease-modifying agents (davunetide, tideglusib) in progressive supranuclear palsy (PSP) failed to show efficacy, but generated data relevant for future trials. METHODS: We provide sample size calculations based on data collec...

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發表在:Mov Disord
Main Authors: Stamelou, Maria, Schöpe, Jakob, Wagenpfeil, Stefan, Ser, Teodoro Del, Bang, Jee, Lobach, Iryna Y., Luong, Phi, Respondek, Gesine, Oertel, Wolfgang H., Boxer, Adam L., Höglinger, Günter U.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289149/
https://ncbi.nlm.nih.gov/pubmed/26948290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.26580
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