Sarco(endo)plasmic reticulum Ca(2)+ ATPase (SERCA) gene silencing and remodeling of the Ca(2)+ signaling mechanism in cardiac myocytes

Transient elevations of cytosolic Ca(2+) are a common mechanism of cellular signaling. In striated muscle, the sarco(endo)plasmic reticulum Ca(2+) ATPase (SERCA) plays an important role in terminating Ca(2+) transients by returning cytosolic Ca(2+) to intracellular stores. Stored Ca(2+)can then be r...

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Detalles Bibliográficos
Autores principales: Seth, M., Sumbilla, C., Mullen, S. P., Lewis, D., Klein, M. G., Hussain, A., Soboloff, J., Gill, D. L., Inesi, G.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC528906/
https://ncbi.nlm.nih.gov/pubmed/15546997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407537101
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