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DynaDom: structure-based prediction of T cell receptor inter-domain and T cell receptor-peptide-MHC (class I) association angles

BACKGROUND: T cell receptor (TCR) molecules are involved in the adaptive immune response as they distinguish between self- and foreign-peptides, presented in major histocompatibility complex molecules (pMHC). Former studies showed that the association angles of the TCR variable domains (Vα/Vβ) can d...

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Detalhes bibliográficos
Publicado no:BMC Struct Biol
Main Authors: Hoffmann, Thomas, Marion, Antoine, Antes, Iris
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289058/
https://ncbi.nlm.nih.gov/pubmed/28148269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-016-0071-7
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