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A novel statistical approach for identification of the master regulator transcription factor

BACKGROUND: Transcription factors are known to play key roles in carcinogenesis and therefore, are gaining popularity as potential therapeutic targets in drug development. A ‘master regulator’ transcription factor often appears to control most of the regulatory activities of the other transcription...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Sikdar, Sinjini, Datta, Susmita
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288875/
https://ncbi.nlm.nih.gov/pubmed/28148240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1499-x
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