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P-Selectin preserves immune tolerance in mice and is reduced in human cutaneous lupus
Mice deficient in P-Selectin presented altered immunity/tolerance balance. We have observed that the absence of P-Selectin promotes splenomegaly with reduced naïve T cell population, elevated activated/effector T cell subset, increased germinal center B and Tfh populations and high production of aut...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5288776/ https://ncbi.nlm.nih.gov/pubmed/28150814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41841 |
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