Reduced GABAergic transmission in the ventrobasal thalamus contributes to thermal hyperalgesia in chronic inflammatory pain

The ventrobasal (VB) thalamus is innervated by GABAergic afferents from the thalamic reticular nucleus (TRN) and participates in nociception. But how the TRN-VB pathway regulates pain is not fully understood. In the present study, we reported decreased extracellular GABA levels in the VB of rats wit...

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Udgivet i:Sci Rep
Main Authors: Zhang, Chan, Chen, Rong-Xiang, Zhang, Yu, Wang, Jie, Liu, Feng-Yu, Cai, Jie, Liao, Fei-Fei, Xu, Fu-Qiang, Yi, Ming, Wan, You
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288727/
https://ncbi.nlm.nih.gov/pubmed/28150719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41439
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