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Bioengineering a bacterial pathogen to assemble its own particulate vaccine capable of inducing cellular immunity
Many bacterial pathogens naturally form cellular inclusions. Here the immunogenicity of polyhydroxyalkanoate (PHA) inclusions and their use as particulate vaccines delivering a range of host derived antigens was assessed. Our study showed that PHA inclusions of pathogenic Pseudomonas aeruginosa are...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5288705/ https://ncbi.nlm.nih.gov/pubmed/28150705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41607 |
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