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Dimethyl Fumarate ameliorates pulmonary arterial hypertension and lung fibrosis by targeting multiple pathways

Pulmonary arterial hypertension (PAH) is a fatal condition for which there is no cure. Dimethyl Fumarate (DMF) is an FDA approved anti-oxidative and anti-inflammatory agent with a favorable safety record. The goal of this study was to assess the effectiveness of DMF as a therapy for PAH using patien...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Grzegorzewska, Agnieszka P., Seta, Francesca, Han, Rong, Czajka, Caitlin A., Makino, Katsunari, Stawski, Lukasz, Isenberg, Jeffrey S., Browning, Jeffrey L., Trojanowska, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288696/
https://ncbi.nlm.nih.gov/pubmed/28150703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41605
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