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Kinetics of Cytotoxic Lymphocytes Reconstitution after Induction Chemotherapy in Elderly AML Patients Reveals Progressive Recovery of Normal Phenotypic and Functional Features in NK Cells

NK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we studied the kinetic of expression of the major activating and inhibitory receptors of NK, CD8 T, and γδ T cells in patients undergoing chemotherapy (CT) for the treatment of AML (n = 29). We showed that NK cells are the ma...

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Publicat a:Front Immunol
Autors principals: Rey, Jérôme, Fauriat, Cyril, Kochbati, Eloïse, Orlanducci, Florence, Charbonnier, Aude, D’Incan, Evelyne, Andre, Pascale, Romagne, François, Barbarat, Bernadette, Vey, Norbert, Olive, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288405/
https://ncbi.nlm.nih.gov/pubmed/28210257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00064
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