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Catechol-O-Methyltransferase gene val158met polymorphism and depressive symptoms during early childhood

Catechol-O-Methyltransferase (COMT) is a critical regulator of catecholamine levels in the brain. A functional polymorphism of the COMT gene, val158met, has been linked to internalizing symptoms (i.e., depression and anxiety) in adolescents and adults. We extended this research by investigating whet...

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Veröffentlicht in:Am J Med Genet B Neuropsychiatr Genet
Hauptverfasser: Sheikh, Haroon I., Kryski, Katie R., Smith, Heather J., Dougherty, Lea R., Klein, Daniel N., Bufferd, Sara J., Singh, Shiva M., Hayden, Elizabeth P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288403/
https://ncbi.nlm.nih.gov/pubmed/23475824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32141
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