Targeting of heme oxygenase-1 attenuates the negative impact of Ikaros isoform 6 in adult BCR-ABL1-positive B-ALL

The correlation between Heme oxygenase-1 (HO-1) and dominant-negative Ikaros isoform 6 (IK6) is unclear. Firstly, we detected that IK6 existed in 20 of 42 (47.6%) adult BCR-ABL1-positive B-lineage acute lymphoblastic leukemia (BCR-ABL1-positive B-ALL) by using reverse transcribed polymerase chain re...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lin, Xiaojing, Zou, Xingli, Wang, Ziming, Fang, Qin, Chen, Shuya, Huang, Jun, Zhe, Nana, Yu, Meisheng, Zhang, Yaming, Wang, Jishi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288214/
https://ncbi.nlm.nih.gov/pubmed/27447561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10725
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