IDO1 involvement in mTOR pathway: a molecular mechanism of resistance to mTOR targeting in medulloblastoma

Medulloblastoma (MB) is the most common malignant brain tumor in children. Despite therapeutic advancements, high-risk groups still present significant mortality. A deeper knowledge of the signaling pathways contributing to MB formation and aggressiveness would help develop new successful therapies....

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Foilsithe in:Oncotarget
Main Authors: Folgiero, Valentina, Miele, Evelina, Carai, Andrea, Ferretti, Elisabetta, Alfano, Vincenzo, Po, Agnese, Bertaina, Valentina, Goffredo, Bianca Maria, Benedetti, Maria Chiara, Camassei, Francesca Diomedi, Cacchione, Antonella, Locatelli, Franco, Mastronuzzi, Angela
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2016
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288157/
https://ncbi.nlm.nih.gov/pubmed/27174915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9284
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