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Multiple defects in translation associated with altered ribosomal protein L4

The ribosomal proteins L4 and L22 form part of the peptide exit tunnel in the large ribosomal subunit. In Escherichia coli, alterations in either of these proteins can confer resistance to the macrolide antibiotic, erythromycin. The structures of the 30S as well as the 50S subunits from each antibio...

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Autori principali: O'Connor, Michael, Gregory, Steven T., Dahlberg, Albert E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC528798/
https://ncbi.nlm.nih.gov/pubmed/15509870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh913
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