Cutaneous HPV8 and MmuPV1 E6 Proteins Target the NOTCH and TGF-β Tumor Suppressors to Inhibit Differentiation and Sustain Keratinocyte Proliferation

Cutaneous beta-papillomaviruses are associated with non-melanoma skin cancers that arise in patients who suffer from a rare genetic disorder, Epidermodysplasia verruciformis (EV) or after immunosuppression following organ transplantation. Recent studies have shown that the E6 proteins of the cancer...

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Опубликовано в: :PLoS Pathog
Главные авторы: Meyers, Jordan M., Uberoi, Aayushi, Grace, Miranda, Lambert, Paul F., Munger, Karl
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287491/
https://ncbi.nlm.nih.gov/pubmed/28107544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006171
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