BET-Inhibitors Disrupt Rad21-Dependent Conformational Control of KSHV Latency

Kaposi’s Sarcoma-associated Herpesvirus (KSHV) establishes stable latent infection in B-lymphocytes and pleural effusion lymphomas (PELs). During latency, the viral genome persists as an epigenetically constrained episome with restricted gene expression programs. To identify epigenetic regulators of...

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Udgivet i:PLoS Pathog
Main Authors: Chen, Horng-Shen, De Leo, Alessandra, Wang, Zhuo, Kerekovic, Andrew, Hills, Robert, Lieberman, Paul M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287475/
https://ncbi.nlm.nih.gov/pubmed/28107481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006100
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