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A Melanoma Lymph Node Metastasis with a Donor-Patient Hybrid Genome following Bone Marrow Transplantation: A Second Case of Leucocyte-Tumor Cell Hybridization in Cancer Metastasis

BACKGROUND: Metastatic disease is the principal cause of mortality in cancer, yet the underlying mechanisms are not fully understood. Macrophage-cancer cell fusion as a cause of metastasis was proposed more than a century ago by German pathologist Prof. Otto Aichel. Since then this theory has been c...

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Publié dans:PLoS One
Auteurs principaux: LaBerge, Greggory S., Duvall, Eric, Grasmick, Zachary, Haedicke, Kay, Pawelek, John
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287451/
https://ncbi.nlm.nih.gov/pubmed/28146572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168581
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