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Low charge and reduced mobility of membrane protein complexes has implications for calibration of collision cross section measurements
Ion mobility mass spectrometry of integral membrane proteins provides valuable insights into their architecture and stability. Here we show that due to their lower charge the average mobility of native-like membrane protein ions is approximately 30 % lower than that of soluble proteins of similar ma...
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| Publicado no: | Anal Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5287392/ https://ncbi.nlm.nih.gov/pubmed/27153188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b00691 |
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