Dissolving microneedles for DNA vaccination: Improving functionality via polymer characterization and RALA complexation

DNA vaccination holds the potential to treat or prevent nearly any immunogenic disease, including cancer. To date, these vaccines have demonstrated limited immunogenicity in vivo due to the absence of a suitable delivery system which can protect DNA from degradation and improve transfection efficien...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Cole, Grace, McCaffrey, Joanne, Ali, Ahlam A., McBride, John W., McCrudden, Cian M., Vincente-Perez, Eva M., Donnelly, Ryan F., McCarthy, Helen O.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287311/
https://ncbi.nlm.nih.gov/pubmed/27846370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1248008
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