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Human Tear Fluid Reduces Culturability of Contact Lens Associated Pseudomonas aeruginosa Biofilms but Induces Expression of the Virulence Associated Type III Secretion System

PURPOSE: The type III secretion system (T3SS) is a significant virulence determinant for Pseudomonas aeruginosa. Using a rodent model, we found that contact lens (CL)-related corneal infections were associated with lens surface biofilms. Here, we studied the impact of human tear fluid on CL-associat...

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Publicat a:Ocul Surf
Autors principals: Wu, Yvonne T., Tam, Connie, Zhu, Lucia S., Evans, David J., Fleiszig, Suzanne M. J.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287294/
https://ncbi.nlm.nih.gov/pubmed/27670247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtos.2016.09.001
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