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Translation from unconventional 5′ start sites drives tumour initiation

We are just beginning to understand how translational control affects tumour initiation and malignancy. Here we use an epidermis-specific, in vivo ribosome profiling strategy to investigate the translational landscape during the transition from normal homeostasis to malignancy. Using a mouse model o...

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Dades bibliogràfiques
Publicat a:Nature
Autors principals: Sendoel, Ataman, Dunn, Joshua G., Rodriguez, Edwin H., Naik, Shruti, Gomez, Nicholas C., Hurwitz, Brian, Levorse, John, Dill, Brian D., Schramek, Daniel, Molina, Henrik, Weissman, Jonathan S., Fuchs, Elaine
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287289/
https://ncbi.nlm.nih.gov/pubmed/28077873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21036
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