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The human initiator is a distinct and abundant element that is precisely positioned in focused core promoters
DNA sequence signals in the core promoter, such as the initiator (Inr), direct transcription initiation by RNA polymerase II. Here we show that the human Inr has the consensus of BBCA(+1)BW at focused promoters in which transcription initiates at a single site or a narrow cluster of sites. The analy...
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| Pubblicato in: | Genes Dev |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5287114/ https://ncbi.nlm.nih.gov/pubmed/28108474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.293837.116 |
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