Učitavanje...
Stabilization of nuclear oncoproteins by RNF4 and the ubiquitin system in cancer
RNF4, a SUMO-targeted ubiquitin ligase, stabilizes a selected group of oncoproteins. It potentiates oncoprotein activity and serves as a positive feedback agonist of Wnt and Notch pathways. RNF4 is essential for cancer cell survival and its levels are elevated in human cancers, correlating with poor...
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| Izdano u: | Mol Cell Oncol |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5287002/ https://ncbi.nlm.nih.gov/pubmed/28197534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1260671 |
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