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Influence of Plasma Cell Niche Factors on the Recruitment and Maintenance of IRF4(hi) Plasma Cells and Plasmablasts in Vaccinated, Simian Immunodeficiency Virus-Infected Rhesus Macaques with Low and High Viremia

In a recent study, we found that protection following simian immunodeficiency virus (SIV) exposure correlated with rectal plasma cell frequency in vaccinated female rhesus macaques. We sought to determine if the same macaques maintained high mucosal plasma cell frequencies postinfection and if this...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Shaw, Julia M., Miller-Novak, Leia K., Mohanram, Venkatramanan, McKinnon, Katherine, Demberg, Thorsten, Vargas-Inchaustegui, Diego A., Venzon, David, Robert-Guroff, Marjorie
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286871/
https://ncbi.nlm.nih.gov/pubmed/27928009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01727-16
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