Increasing Type 1 Poliovirus Capsid Stability by Thermal Selection

Poliomyelitis is a highly infectious disease caused by poliovirus (PV). It can result in paralysis and may be fatal. Integrated global immunization programs using live-attenuated oral (OPV) and/or inactivated (IPV) PV vaccines have systematically reduced its spread and paved the way for eradication....

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Bibliographic Details
Published in:J Virol
Main Authors: Adeyemi, Oluwapelumi O., Nicol, Clare, Stonehouse, Nicola J., Rowlands, David J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286869/
https://ncbi.nlm.nih.gov/pubmed/27928008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01586-16
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