Discoidin domain receptor 1 activity drives an aggressive phenotype in gastric carcinoma

BACKGROUND: Discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase that utilizes collagen as a ligand, is a key molecule in the progression of solid tumors as it regulates the interaction of cancer cells with the tumor stroma. However, the clinical relevance of DDR1 expression in gastric car...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Hur, Hoon, Ham, In-Hye, Lee, Dakeun, Jin, Hyejin, Aguilera, Kristina Y., Oh, Hye Jeong, Han, Sang-Uk, Kwon, Ji Eun, Kim, Young-Bae, Ding, Ke, Brekken, Rolf A.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286810/
https://ncbi.nlm.nih.gov/pubmed/28143619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3051-9
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