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Upregulation of MiR-205 transcriptionally suppresses SMAD4 and PTEN and contributes to human ovarian cancer progression

MicroRNAs (miRNAs) function as critical regulators of gene expression and their deregulation is associated with the development and progression of various cancers. This study aimed to investigate the biological role and mechanism of miR-205 in ovarian cancer (OC). MiR-205 was upregulated in OC tissu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Juanni, Hu, Kuan, Gong, Guanghui, Zhu, Ding, Wang, Yixuan, Liu, Hailing, Wu, Xiaoying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286557/
https://ncbi.nlm.nih.gov/pubmed/28145479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41330
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