Nup358 binds to AGO proteins through its SUMO‐interacting motifs and promotes the association of target mRNA with miRISC

MicroRNA (miRNA)‐guided mRNA repression, mediated by the miRNA‐induced silencing complex (miRISC), is an important component of post‐transcriptional gene silencing. However, how miRISC identifies the target mRNA in vivo is not well understood. Here, we show that the nucleoporin Nup358 plays an impor...

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Detaylı Bibliyografya
Yayımlandı:EMBO Rep
Asıl Yazarlar: Sahoo, Manas Ranjan, Gaikwad, Swati, Khuperkar, Deepak, Ashok, Maitreyi, Helen, Mary, Yadav, Santosh Kumar, Singh, Aditi, Magre, Indrasen, Deshmukh, Prachi, Dhanvijay, Supriya, Sahoo, Pabitra Kumar, Ramtirtha, Yogendra, Madhusudhan, Mallur Srivatsan, Gayathri, Pananghat, Seshadri, Vasudevan, Joseph, Jomon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286382/
https://ncbi.nlm.nih.gov/pubmed/28039207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642386
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