Monoacylglycerol lipase inhibitors produce pro- or antidepressant responses via hippocampal CA1 GABAergic synapses

The probability of suffering the mood disorder depression is up to 30% in women and 15% in men during their life span. Pharmacological options for depression are limited: conventional antidepressants have low efficacy and a delayed onset of action (several weeks). Here we investigate the antidepress...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Wang, Y, Gu, N, Duan, T, Kesner, P, Blaskovits, F, Liu, J, Lu, Y, Tong, L, Gao, F, Harris, C, Mackie, K, Li, J, Tan, Q, Hill, M N, Yuan, Z, Zhang, X
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285470/
https://ncbi.nlm.nih.gov/pubmed/27001616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.22
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