Tamoxifen Activation of Cre-Recombinase Has No Persisting Effects on Adult Neurogenesis or Learning and Anxiety

Adult neurogenesis is a tightly regulated process continuously taking place in the central nervous system of most mammalian species. In neuroscience research, transgenic animals bearing the tamoxifen-inducible CreER(T2)-Lox system are widely used. In this study, we made use of a Nestin-CreER(T2)/R26...

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Bibliografske podrobnosti
izdano v:Front Neurosci
Main Authors: Rotheneichner, Peter, Romanelli, Pasquale, Bieler, Lara, Pagitsch, Sebastian, Zaunmair, Pia, Kreutzer, Christina, König, Richard, Marschallinger, Julia, Aigner, Ludwig, Couillard-Després, Sébastien
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285339/
https://ncbi.nlm.nih.gov/pubmed/28203140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00027
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