The Major Immediate-Early Protein IE2 of Human Cytomegalovirus Is Sufficient to Induce Proteasomal Degradation of CD83 on Mature Dendritic Cells

Human cytomegalovirus (HCMV) is the prototypic beta-herpesvirus and widespread throughout the human population. While infection is asymptomatic in healthy individuals, it can lead to high morbidity and mortality in immunocompromised persons. Importantly, HCMV evolved multiple strategies to interfere...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Heilingloh, Christiane S., Grosche, Linda, Kummer, Mirko, Mühl-Zürbes, Petra, Kamm, Lisa, Scherer, Myriam, Latzko, Melanie, Stamminger, Thomas, Steinkasserer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285329/
https://ncbi.nlm.nih.gov/pubmed/28203230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00119
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