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Targeted pulmonary delivery of inducers of host macrophage autophagy as a potential host-directed chemotherapy of tuberculosis()

One of the promising host-directed chemotherapeutic interventions in tuberculosis (TB) is based on inducing autophagy as an immune effector. Here we consider the strengths and weaknesses of potential autophagy-based pharmacological intervention. Using the existing drugs that induce autophagy is an o...

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Detalhes bibliográficos
Publicado no:Adv Drug Deliv Rev
Main Authors: Gupta, Anuradha, Misra, Amit, Deretic, Vojo
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285306/
https://ncbi.nlm.nih.gov/pubmed/26829287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2016.01.016
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