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Identification of the staphylococcal enterotoxin A superantigen binding site in the beta 1 domain of the human histocompatibility antigen HLA-DR.

The staphylococcal enterotoxin A (SEA) is a superantigen that must bind to class II molecules of the major histocompatibility complex to be recognized by T cells. In humans, most HLA-DR class II allelic and isotypic forms, such as DR1, bind SEA well. DRw53 is an exception, binding SEA very poorly. W...

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Bibliografiska uppgifter
Huvudupphovsmän: Herman, A, Labrecque, N, Thibodeau, J, Marrack, P, Kappler, J W, Sekaly, R P
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1991
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC52845/
https://ncbi.nlm.nih.gov/pubmed/1946464
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