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Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging

Increasing evidence from epidemiological, clinical and experimental studies indicate that age-related cerebromicrovascular dysfunction and microcirculatory damage play critical roles in the pathogenesis of many types of dementia in the elderly, including Alzheimer’s disease. Understanding and target...

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Опубликовано в: :Am J Physiol Heart Circ Physiol
Главные авторы: Toth, Peter, Tarantini, Stefano, Csiszar, Anna, Ungvari, Zoltan
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283909/
https://ncbi.nlm.nih.gov/pubmed/27793855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00581.2016
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