Obesity, type 2 diabetes, and impaired insulin-stimulated blood flow: role of skeletal muscle NO synthase and endothelin-1

Increased endothelin-1 (ET-1) and reduced endothelial nitric oxide phosphorylation (peNOS) are hypothesized to reduce insulin-stimulated blood flow in type 2 diabetes (T2D), but studies examining these links in humans are limited. We sought to assess basal and insulin-stimulated endothelial signalin...

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Publicat a:J Appl Physiol (1985)
Autors principals: Reynolds, Leryn J., Credeur, Daniel P., Manrique, Camila, Padilla, Jaume, Fadel, Paul J., Thyfault, John P.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283852/
https://ncbi.nlm.nih.gov/pubmed/27789766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00286.2016
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