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Inference of Candidate Germline Mutator Loci in Humans from Genome-Wide Haplotype Data

The rate of germline mutation varies widely between species but little is known about the extent of variation in the germline mutation rate between individuals of the same species. Here we demonstrate that an allele that increases the rate of germline mutation can result in a distinctive signature i...

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Bibliografiset tiedot
Julkaisussa:PLoS Genet
Päätekijät: Seoighe, Cathal, Scally, Aylwyn
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283766/
https://ncbi.nlm.nih.gov/pubmed/28095480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006549
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