Determination of plasma concentrations of levofloxacin by high performance liquid chromatography for use at a multidrug-resistant tuberculosis hospital in Tanzania

Therapeutic drug monitoring may improve multidrug-resistant tuberculosis (MDR-TB) treatment outcomes. Levofloxacin demonstrates significant individual pharmacokinetic variability. Thus, we sought to develop and validate a high-performance liquid chromatography (HPLC) method with ultraviolet (UV) det...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Ebers, Andrew, Stroup, Suzanne, Mpagama, Stellah, Kisonga, Riziki, Lekule, Isaack, Liu, Jie, Heysell, Scott
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283651/
https://ncbi.nlm.nih.gov/pubmed/28141813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170663
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