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Inhibition of tumor growth and metastasis by EMMPRIN multiple antigenic peptide (MAP) vaccination is mediated by immune modulation

Previously, we have identified a new epitope in EMMPRIN, a multifunctional protein that mediates tumor cell–macrophage interactions and induces both MMP-9 and VEGF. Here, we synthesized this epitope as an octa-branched multiple antigenic peptide (MAP) to vaccinate mice implanted with subcutaneous sy...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Simanovich, Elina, Brod, Vera, Rahat, Maya M., Drazdov, Ella, Walter, Miriam, Shakya, Jivan, Rahat, Michal A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283626/
https://ncbi.nlm.nih.gov/pubmed/28197388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1261778
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