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Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota

The gut microbiota influences the development and progression of metabolic diseases partly by metabolism of bile acids (BAs) and modified signaling through the farnesoid X receptor (FXR). In this study, we aimed to determine how the human gut microbiota metabolizes murine BAs and affects FXR signali...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Wahlström, Annika, Kovatcheva-Datchary, Petia, Ståhlman, Marcus, Khan, Muhammad-Tanweer, Bäckhed, Fredrik, Marschall, Hanns-Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282957/
https://ncbi.nlm.nih.gov/pubmed/27956475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M072819
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