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Preferential hydrolysis of truncated oxidized glycerophospholipids by lysosomal phospholipase A2

Truncated oxidized glycerophospholipids (ox-PLs) are bioactive lipids resulting from oxidative stress. The catabolic pathways for truncated ox-PLs are not fully understood. Lysosomal phospholipase A2 (LPLA2) with phospholipase A and transacylase activities is a key enzyme in phospholipid homeostasis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Lipid Res
Hauptverfasser: Abe, Akira, Hiraoka, Miki, Ohguro, Hiroshi, Tesmer, John J., Shayman, James A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282950/
https://ncbi.nlm.nih.gov/pubmed/27993948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M070730
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