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Antibody structure determination using a combination of homology modeling, energy-based refinement, and loop prediction

We present the blinded prediction results in the Second Antibody Modeling Assessment (AMA-II) using a fully automatic antibody structure prediction method implemented in the programs BioLuminate and Prime. We have developed a novel knowledge based approach to model the CDR loops, using a combination...

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Dades bibliogràfiques
Publicat a:Proteins
Autors principals: Zhu, Kai, Day, Tyler, Warshaviak, Dora, Murrett, Colleen, Friesner, Richard, Pearlman, David
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282925/
https://ncbi.nlm.nih.gov/pubmed/24619874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24551
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