Natural underlying mtDNA heteroplasmy as a potential source of intra‐person hiPSC variability

Functional variability among human clones of induced pluripotent stem cells (hiPSCs) remains a limitation in assembling high‐quality biorepositories. Beyond inter‐person variability, the root cause of intra‐person variability remains unknown. Mitochondria guide the required transition from oxidative...

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Foilsithe in:EMBO J
Main Authors: Perales‐Clemente, Ester, Cook, Alexandra N, Evans, Jared M, Roellinger, Samantha, Secreto, Frank, Emmanuele, Valentina, Oglesbee, Devin, Mootha, Vamsi K, Hirano, Michio, Schon, Eric A, Terzic, Andre, Nelson, Timothy J
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282833/
https://ncbi.nlm.nih.gov/pubmed/27436875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694892
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