High-dimensional assessment of B-cell responses to quadrivalent meningococcal conjugate and plain polysaccharide vaccine

BACKGROUND: Neisseria meningitidis is a globally important cause of meningitis and septicaemia. Twelve capsular groups of meningococci are known, and quadrivalent vaccines against four of these (A, C, W and Y) are available as plain-polysaccharide and protein-polysaccharide conjugate vaccines. Here...

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Veröffentlicht in:Genome Med
Hauptverfasser: O’Connor, Daniel, Clutterbuck, Elizabeth A., Thompson, Amber J., Snape, Matthew D., Ramasamy, Maheshi N., Kelly, Dominic F., Pollard, Andrew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282650/
https://ncbi.nlm.nih.gov/pubmed/28137280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0400-x
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